Tag: TRD augmentation

Treatment-Resistant Depression: Augmentation and Advanced Therapies That Actually Work

Treatment-Resistant Depression: Augmentation and Advanced Therapies That Actually Work
2 February 2026 Shaun Franks

Treatment-resistant depression affects 30-40% of people with major depression. Learn how augmentation with medications like aripiprazole and esketamine, plus advanced therapies like rTMS, can help when standard antidepressants fail.