Tendon Rupture: Causes, Risks, and What to Do When It Happens

When a tendon rupture, a complete tear of the tissue connecting muscle to bone. Also known as tendon tear, it doesn’t always come with a loud pop—sometimes it’s just sudden weakness or pain that won’t go away. This isn’t just a sports injury. People on long-term steroids, older adults with arthritis, and even those taking certain antibiotics like ciprofloxacin can wake up one day unable to push off their foot or lift their arm. The Achilles tendon, the thick band behind the ankle that lets you walk, run, and jump. is the most common site, but the rotator cuff, the group of tendons in the shoulder that stabilize the joint. tears are just as disabling—and often missed until it’s too late for simple rehab.

Tendon rupture doesn’t happen out of nowhere. It’s usually the last step in a long decline. Years of overuse, poor blood flow to the area, or chronic inflammation from conditions like diabetes or rheumatoid arthritis weaken the tissue. Then something small—a missed step, a heavy lift, even a cough—snaps it. Medications can speed this up. Corticosteroid injections, while great for short-term pain, reduce collagen production and make tendons brittle. Fluoroquinolone antibiotics like Levaquin and Cipro are linked to tendon damage, especially in people over 60. And if you’re on long-term prednisone? Your tendons are under constant stress. Recovery isn’t just about rest. It’s about timing. Waiting too long to treat it means scar tissue forms, and surgery becomes the only option. But even then, full strength rarely comes back without months of physical therapy.

What you’ll find here aren’t generic advice lists. These are real cases: the runner who ignored calf pain until his Achilles gave out mid-stride, the woman on prednisone for lupus who couldn’t lift her coffee cup after a minor fall, the man who got a flu shot and ended up with a torn rotator cuff. Each post dives into what actually works—what to avoid, which drugs increase risk, how to spot early warning signs, and what rehab looks like when the tendon is already gone. There’s no fluff. Just what you need to know before it’s too late.

Fluoroquinolones and Tendon Rupture: What You Need to Know About the Risks

Fluoroquinolones and Tendon Rupture: What You Need to Know About the Risks
1 December 2025 Shaun Franks

Fluoroquinolone antibiotics like ciprofloxacin and levofloxacin carry a serious risk of tendon rupture, especially in older adults and those on steroids. Learn the signs, who's most at risk, and what to do if you're prescribed one.